The American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine have long supported the short-term (usually less than 48hrs) use of MAGNESIUM SULFATE in obstetric care is appropriate for certain conditions and durations of treatment including:
-the prevention and treatment of seizures in women with preeclampsia or eclampsia.
-fetal neuroprotection before anticipated early preterm(less than 32 weeks of gestation) delivery, and
-short term prolongation of pregnancy(up to 48 hours) to allow antenatal corticosteroid administration to pregnant women at risk for preterm delivery within 7 days.
However, the U.S. Food and Drug Administration advises against the use of magnessium sulfate injection for more than 5-7 days to stop preterm labour in pregnant women as it is unindicated and nonstandard.